Amazing Spider-Man (1963 1st Series) #336
"The Wagers of Sin" The Return of the Sinister Six Part 3 of 6. Script by David Michelinie. Pencils by Erik Larsen. Inks by Mike Machlan. Cover by Erik Larsen and Bob Wiacek. Nathan Lubensky has been a gambler his whole life! And before Aunt May's fiancé shuffles off his mortal coil, he's going all-in one final time! Strangely enough New York bookies are taking action on whether an Atlantic City casino owner will be successfully assassinated! Nathan is sure the casino owner is a goner! But he doesn't know that the Vulture, Chance, and Spider-Man will play a part in the fateful hit! All the cards are on the table! Is Nathan going to lose everything? A heartbreaking ending. Death of Nathan Lubensky. Cameo appearances by Doctor Strange, Mary Jane Watson, Doctor Octopus, and the Kingpin.